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the discovery of our peptide

the discovery of our peptide

A team of European researchers led by noted biotechnologist, Prof Artur M. Cavaco-Paulo were researching the glycoproteins synthesized in the epithelial cells of the lungs. One of the protein fragments of Surfactant Protein D (SP-D) had a unique ability to diffuse through the lipids (also present in the innermost layers of our hair) and bind with lipophilic proteins such as keratin. Using hydrophyllic/hydrophobic balance ratios, he then tried to find a similar protein in the human keratin genome and it surprisingly worked better than the SP-D segment.

 

Inspired by this discovery, Prof Artur and his team scanned the entire active protein expression of the human keratin genome to identify all protein fragments with multiple cysteines that could bind very well with the keratin associated proteins (KAP) in our hair. The KAPs play a crucial role in forming a strong hair shaft through a cross linked network with keratin intermediate filaments (KIFs) and polypeptide chains formed by KAP1 /KAP II keratins.

 

After extensive research that lasted several years, the K18Peptide™ sequence assembly was developed and patented – it is the longest chain peptide that can penetrate into the hair cortex to reconnect polypeptide chains broken by alkali and chemical processing with the free thiol from cysteine inside the K18 peptide also participating in intra and inter exchange of dilsulfide bonds to reconform any cleaved disulfide bonds within the same molecular chain.”

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Pro Distribution Partners

Hair professionals can shop wholesale at the following distributors. Professionals within the US will also be able to shop directly from K18hair.com starting early 2021! Check back again soon for updates as we continue to expand globally.



Questions? Email us at hello@k18hair.com

Paramount Beauty Supply
USA
Salon Services Pro
USA
Salon Service Group
USA
Salonwax Pro
USA
Premier Beauty Supply
USA
Launching Soon
Ozdare - Australia
AU
 
Launching Soon
American Crew Ltd. - New Zealand
NZ
 
Launching Soon
PlayGround - Hong Kong
HK
 
Launching Soon
Session Map - Sweden
SE
 
Launching Soon
Cyprus
CY
 
Launching Soon
Belgium
BE
 
Coming Early 2021
Canada
CA
 
Coming Early 2021
Czech Republic
CZ
 
Coming Early 2021
Finland
FI
 
Coming Early 2021
France
FR
 
Coming Early 2021
Germany
DE
 
Coming Early 2021
Ireland
IR
 
Coming Early 2021
Italy
IT
 
Coming Early 2021
Netherlands
NL
 
Coming Early 2021
Norway
NO
 
Coming Early 2021
Singapore
SG
 
Coming Early 2021
Taiwan
TW
 
Coming Early 2021
UK
UK
 
Coming Early 2021
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